216.73.216.252===--UPDATE `0-usmeigara` SET site='',name='',jigyoyoyaku='',sijyo='',gyosyu='',honten='',industry='',sector='',haishi='',keyword='' where code = 'arav'---select * from `0-usmeigara` WHERE code='arav'
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arav
銘柄登録／業種登録　関連銘柄専用コメ／リスト／日本株
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その鉛産物候補は、プラチナ耐性再発性卵巣癌の治療のための第III相臨床試験であるGas6-axlシグナル伝達経路を標的とする超親和性のデコイタンパク質であるBatiraxceptです。同社はまた、Gas6-axlシグナル伝達経路の活性化をブロックする可溶性FC融合タンパク質であるAVB-S6を開発しています。Aravive、Inc。
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日本語に翻訳して１５０文字程度で要約を。語尾は「している」等の常体で
「Aravive, Inc., a clinical-stage biopharmaceutical company, develops transformative treatments for life-threatening diseases, including cancer and fibrosis in the United States. Its lead product candidate is batiraxcept, an ultrahigh-affinity, decoy protein that targets the GAS6-AXL signaling pathway, which is in Phase III clinical trial for the treatment of platinum- resistant recurrent ovarian cancer; and in Phase Ib/II clinical trial for the treatment of clear cell renal cell carcinoma and pancreatic adenocarcinoma. The company also develops AVB-S6, a soluble Fc-fusion protein to block the activation of the GAS6-AXL signaling pathway. It has a license and collaboration agreement with WuXi Biologics (Hong Kong) Limited to identify and develop novel high-affinity bispecific antibodies targeting cancer and fibrosis; and license agreement with 3D Medicines Inc. to develop products that contain batiraxcept as the sole drug substance for the treatment of human oncological diseases in mainland China, Taiwan, Hong Kong, and Macau. The company was formerly known as Versartis, Inc. and changed its name to Aravive, Inc. in October 2018. Aravive, Inc. was incorporated in 2008 and is headquartered in Houston, Texas.」